Cancer is a notoriously complex disease, in part because it may be caused by mutations among hundreds or even thousands of genes. In addition, most cancers exhibit an extraordinary amount of variation among genetic mutations, ...
Jan 15, 2021
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Researchers at Tohoku University have revealed further insight into the fetal development of our brain and the potential causes of fragile X syndrome (FSX).
Dec 16, 2020
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Young children of African ancestry are more at risk of developing obesity if they possess a genetic variant that reduces their ability to produce the hormone leptin. Adults with the variant do not have the same risk, suggesting ...
Nov 23, 2020
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Fanconi anemia (FA) is a genetic disease affecting small children characterized by bone-marrow failure, developmental abnormalities and predisposition to multiple forms of cancer. The molecular mechanisms behind FA are inherited ...
Oct 14, 2020
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Large-scale studies examining RNA transcripts produced by genomes under specific circumstances or in specific cell populations, also known as transcriptomic studies, have recently led to fascinating new observations. These ...
Biological sex has a small but ubiquitous influence on gene expression in almost every type of human tissue, reports a new study from Northwestern Medicine, the University of Chicago and the Centre for Genomic Regulation ...
Sep 10, 2020
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A series of papers published recently by two teams of vision researchers at the University at Buffalo and the University of Alabama at Birmingham (UAB) is revealing important new information about the possible cause of a ...
Jun 24, 2020
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Our cells have several ways to repair DNA that breaks when the cells divide. However, genetic mutations can disable these DNA repair mechanisms, destabilize the cells, and trigger cancer. In a paper published today in the ...
Jun 4, 2020
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Scientists at the UNC School of Medicine and colleagues created a new computational tool called H-MAGMA to study the genetic underpinnings of nine brain disorders, including the identification of new genes associated with ...
Mar 9, 2020
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A study led by the IBB-UAB has identified the molecular mechanism through which a protein carrying genetic mutations associated with limb-girdle muscular dystrophy type 1G accelerates its tendency to form amyloid fibrils ...
Jan 29, 2020
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