Psychology & Psychiatry

New findings link brain's immune system to psychosis

New research at Karolinska Institutet in Sweden suggests a link between psychosis and a genetic change that affects the brain's immune system. The study published in Molecular Psychiatry may impact the development of modern ...

Oncology & Cancer

New maps link thousands of genetic variants to disease genes

Genome-wide association studies (GWAS) have identified thousands of genetic variants that are associated with a wide range of diseases. But these studies often fall short of establishing what a genetic variant does to bring ...

Oncology & Cancer

Case study of rare nervous system tumor reveals hypermutation

While deadly, gliosarcomas are a rare central nervous system tumor often overshadowed in research by more common tumors. These sarcomas can occur either in the brain or the spine (the latter is much less common).

Medical research

New statistical method eases data reproducibility crisis

A reproducibility crisis is ongoing in scientific research, where many studies may be difficult or impossible to replicate and thereby validate, especially when the study involves a very large sample size. For example, to ...

Diseases, Conditions, Syndromes

Scientists develop vaccine strategy for urinary tract infections

Anyone who has ever developed a urinary tract infection (UTI) knows that it can be painful, pesky and persistent. UTIs have a high recurrence rate and primarily afflict women—as many as 50% of women will experience at least ...

Genetics

Sequence African genomes for Africa and the world: scientist

A $4.5 billion initiative to sequence the genomes of three million Africans would not only benefit a continent long neglected in gene-based healthcare, but advance understanding of genetic disease worldwide, the project leader ...

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