Oncology & Cancer

Tumor mutations may predict response to immunotherapy

Mismatch repair deficiency refers to a characteristic of some cancer cells that create a large number of mutations, or changes, in certain genes when their mismatch repair proteins are unable to correct mistakes made when ...

Immunology

Mutation behind incurable disease mapped

Researchers at Karolinska Institutet have mapped the genetic mutation behind the incurable disease systemic mastocytosis. The results give insights into the origin of the disease, and the researchers also discovered a protein ...

Medical research

Creating blood vessels on demand

When organs or tissues are damaged, new blood vessels must form as they play a vital role in bringing nutrients and eliminating waste and it is necessary for organs and tissues to regain their normal function. At present, ...

Oncology & Cancer

Precision oncology insights revealed for colorectal cancer

Next-generation sequencing of tumor DNA from patients with colorectal cancer revealed genetic alterations that were linked to different survival and treatment outcomes in an analysis led by a University of North Carolina ...

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