Genetics

New genetic clues emerge on origin of Hirschsprung's disease

Genetic studies in humans, zebrafish and mice have revealed how two different types of genetic variations team up to cause a rare condition called Hirschsprung's disease. The findings add to an increasingly clear picture ...

Oncology & Cancer

Step closer to predicting cancer patients' drug toxicity

Being able to predict that a patient will adversely react to a drug that's meant to be treating them is a key aim of personalised medicine, and could help to improve the patient's overall treatment.

Diseases, Conditions, Syndromes

Study maps travel of H7 influenza genes

Influenza has a long history of being one of the most deadly diseases to afflict humanity, but what exactly makes it so dangerous?

HIV & AIDS

New study reveals why some people may be immune to HIV-1

Doctors have long been mystified as to why HIV-1 rapidly sickens some individuals, while in others the virus has difficulties gaining a foothold. Now, a study of genetic variation in HIV-1 and in the cells it infects reported ...

Genetics

Whole-exome sequencing shows potential as diagnostic tool

Among a group of 2,000 patients referred for evaluation of suspected genetic conditions, whole-exome sequencing provided a potential molecular diagnosis for 25 percent, including detection of a number of rare genetic events ...

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