Immunology

The wrong track: How papillomaviruses trick the immune system

Specific antibodies protect us against viral infections—or do they? Researchers at the German Cancer Research Center (DKFZ) studied the immune response to papillomaviruses in mice and discovered a hitherto unknown mechanism ...

Diseases, Conditions, Syndromes

A coronavirus vaccine may require boosters – here's what that means

In the global race to contain the coronavirus pandemic, there is hopeful news on the vaccine front, with a number of potential candidates being developed and some promising early results. Based on what we know so far, it ...

Diseases, Conditions, Syndromes

Genetic mutations predispose individuals to severe COVID-19

Current observations suggest that the coronavirus SARS-CoV-2 causes severe symptoms mainly in elderly patients with chronic disease. However when two pairs of previously healthy young brothers from two families required mechanical ...

Oncology & Cancer

Genes that predispose to cancer by impairing the immune system

The idea that the immune system 'monitors and prevents' the development of cancer, which is called 'cancer immune vigilance," was initially proposed at the beginning of the last century. Since then, epidemiological studies ...

Immunology

A novel mechanism that triggers a cellular immune response

Viruses and other disease-causing microbes influence the type of immune response their hosts will develop against them. In some cases, the predominant response involves antibodies, proteins made by the immune system that ...

Diseases, Conditions, Syndromes

Protecting the injured kidney

The proximal tubule—part of the kidney's nephron—is a target of acute kidney injury (AKI), and its response to injury determines whether the kidney undergoes repair or progresses to chronic kidney disease (CKD).

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