Medical research

New statistical method eases data reproducibility crisis

A reproducibility crisis is ongoing in scientific research, where many studies may be difficult or impossible to replicate and thereby validate, especially when the study involves a very large sample size. For example, to ...

Health

Eight ways chemical pollutants harm the body

A new review of existing evidence proposes eight hallmarks of environmental exposures that chart the biological pathways through which pollutants contribute to disease: oxidative stress and inflammation, genomic alterations ...

Oncology & Cancer

New computational method detects disrupted pathways in cancer

Cancer is a notoriously complex disease, in part because it may be caused by mutations among hundreds or even thousands of genes. In addition, most cancers exhibit an extraordinary amount of variation among genetic mutations, ...

Genetics

Why we differ in our ability to fight off gut infections

Τhe ability of the immune system to fight off bacterial, viral and other invading agents in the gut differs between individuals. However, the biological mechanism by which this happens is not well understood, but at least ...

Genetics

Researchers report the function of reverse-twisting DNA

Normally, the two strands of the DNA double helix wind around each other in a right-handed spiral. However, there is another conformation called Z-DNA in which the strands twist to the left. The function of Z-DNA has remained ...

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