A new study led by researchers at the University of North Carolina at Chapel Hill has found that that using a polygenic risk score (PRS) based on data from genome-wide association studies (GWAS) improves psychosis risk prediction ...
Nov 12, 2019
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Researchers have identified 57 genetic variations of a gene strongly associated with declines in blood oxygen levels during sleep. Low oxygen levels during sleep are a clinical indicator of the severity of sleep apnea, a ...
Oct 24, 2019
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Atrial fibrillation is the most common heart arrhythmia in humans. This condition increases the risk of heart failure, stroke, dementia and death, and current treatments have suboptimal efficacy and carry side effects. Looking ...
Oct 21, 2019
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Researchers are exploring the cause and effect relationships between common health indicators and lifespan, by analyzing polygenic risk scores (PRS), a numerical score of a person's risk for disease based on multiple genetic ...
Oct 17, 2019
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Scientists have assembled a set of genetic sequences that enable the reference genome to better reflect global genetic diversity. The new sequences improve the utility of the human reference genome, a touchstone resource ...
Oct 16, 2019
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Researchers have implicated 10 new genes in the development of schizophrenia using a method called whole exome sequencing, the analysis of the portion of DNA that codes for proteins. Working with a global consortium of schizophrenia ...
Oct 16, 2019
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Few areas of science have seen such a dramatic development in the last decade as genomics. It is now possible to read the genomes of millions of people in so-called genome-wide association studies. These studies have identified ...
Oct 15, 2019
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Broadening diversity among participants in human genomics research will maximize its potential to discover causes and possible treatments of diseases, requiring thoughtful study design and methodological considerations, write ...
Oct 10, 2019
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Genome-wide association studies have uncovered more than 500 genetic variants linked to heart function, everything from heart rate to irregular rhythms that can lead to stroke, heart failure or other complications. But since ...
Sep 30, 2019
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Genetic research led by Queen Mary University of London could open the way to earlier identification of people at risk of heart failure and to the development of new treatments.
Sep 26, 2019
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