Genetics

New gene variants associated with chronic back pain

Chronic back pain is the number one cause of years lived with disability worldwide. In a new study, Pradeep Suri of the Department of Veterans Affairs in Seattle, Washington, and colleagues in the United States and Europe, ...

Genetics

Genetic determinants of telomere length in African American youth

Telomeres are DNA-protein structures that play a vital role in maintaining DNA stability and integrity. Telomere length (TL) is an important biomarker of aging and overall health, but TL has been mostly studied in adult populations ...

Genetics

Does genome sequencing increase downstream costs?

As genome sequencing enters the clinic, fears have arisen about its potential to motivate follow-up testing and ongoing screening that could drastically increase health care spending. But few studies have quantified the downstream ...

Cardiology

Gene therapy using 'junk DNA' could lower risk for heart disease

Scientists from UCLA and the Howard Hughes Medical Institute successfully used a gene that suppresses cholesterol levels as part of a treatment to reduce plaque in mice with a disorder called familial hypercholesterolemia. ...

Medical research

Eye melanoma, media hype, and genomic medicine

Melanoma of the eye presents a case study in the value of diagnosing by phenotype (symptoms and physical presentation) versus assessing risk genotype – a discussion that may impact ongoing efforts to sequence gazillions ...

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