A new study looking at the genomes of more than 1,500 patients with idiopathic pulmonary fibrosis, a rare and devastating lung disease, found multiple genetic associations with the disease, including one gene variant that ...
Apr 16, 2013
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Researchers from the MRC Centre for Virus Research at the University of Glasgow in Scotland have developed methods to synthesize and change the genome of Schmallenberg virus (SBV). SBV is a recently discovered pathogen of ...
Jan 10, 2013
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Researchers have discovered a mechanism for COVID-19 susceptibility using a newly created tool. The tool, GASPACHO, captures dynamic changes in gene expression along the innate immune response, allowing researchers to identify ...
Jun 15, 2023
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Asthma patients experience respiratory distress due to allergens like house dust mites or pollen. However, the various triggers for asthma share a common pathway involving the release of proteins called type-2 cytokines by ...
Jun 24, 2024
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Oncolytic virology uses live viruses to sense the genetic difference between a tumor and normal cell. Once the virus finds a tumor cell, it replicates inside that cell, kills it and then spreads to adjacent tumor cells to ...
Oct 18, 2011
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Prostate cancer tumors harboring BRCA1/2 mutations are exceptionally sensitive to PARP inhibitors, while genomic alterations in other DNA damage response (DDR) genes are less responsive. To identify previously unknown genes ...
Apr 4, 2023
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A team of scientists led by virologists Prof. Oliver T. Fackler and Prof. Oliver T. Keppler from Heidelberg University Hospital have decoded a mechanism used by the human immune system to protect itself from HIV viruses. ...
Oct 2, 2012
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Mammalian DNA, including the human genome, contains about 1 million SINEs (short interspersed nuclear elements), noncoding mobile genetic elements that make up about 10% of the total genome. SINEs are normally silent, though ...
Nov 19, 2015
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Biomarker testing surveys specific disease-associated molecules to predict treatment response and disease progression; however its use has complicated the diagnosis of non-small-cell lung cancer (NSCLC). In a new study in ...
Mar 15, 2021
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Scientists of the Max F. Perutz Laboratories of the University of Vienna and the Medical University of Vienna, together with colleagues of the ETH Zurich, have now shown how double stranded RNA, such as viral genetic information, ...
Apr 22, 2014
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