Oncology & Cancer
Algorithm offers new way to spot patients likely to respond to immunotherapy
Scientists have developed a new way of using cancers' DNA to spot cancer patients who may benefit from immunotherapy.
Mar 10, 2023
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Page 2 - News tagged with genomic response
Oncology & Cancer
Two genomic studies could yield more effective, less toxic immunotherapies
Mnemo Therapeutics, a biotechnology company developing transformational immunotherapies, has announced publication of two scientific studies developed at Institut Curie, its closest academic collaborator, in the journal Science ...
Feb 3, 2023
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HIV & AIDS
Immune system uses two-step verification to defend against HIV
Human immunodeficiency virus 1, more commonly known as HIV-1, is known for its uncanny ability to evade the immune system. Scientists at Scripps Research and collaborators have now uncovered how our innate immune system—the ...
Jul 8, 2022
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Inflammatory disorders
DNA building blocks regulate inflammation
Mitochondria are the energy suppliers of our body cells. These tiny cell components have their own genetic material, which triggers an inflammatory response when released into the interior of the cell. The reasons for the ...
Apr 30, 2021
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Genetics
'Jumping' DNA regulates human neurons
The human genome contains over 4.5 million sequences of DNA called "transposable elements," virus-like entities that "jump" around and help regulate gene expression. They do this by binding transcription factors, which are ...
Aug 31, 2020
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HIV & AIDS
Unique HIV reservoirs in elite controllers
Xu Yu, MD, Ragon group leader, recently published a study entitled "Distinct viral reservoirs in individuals with spontaneous control of HIV-1," in Nature. Yu's lab, in collaboration with Ragon group leaders Mathias Lichterfeld, ...
Aug 26, 2020
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Genetics
3-D shape of human genome essential for robust inflammatory response
The three-dimensional structure of the human genome is essential for providing a rapid and robust inflammatory response, but is surprisingly not vital for reprogramming one cell type into another, according to research published ...
Jun 8, 2020
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Diseases, Conditions, Syndromes
New vaccines protect against COVID-19 in non-human primates, study finds
With nearly 5 million confirmed cases globally and more than 300,000 deaths from COVID-19, much remains unknown about SARS-CoV-2, the virus that causes the disease. Two critical questions are whether vaccines will prevent ...
May 20, 2020
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Medical research
New study reveals an innate genome immune response to retroviruses in koalas
A new study from researchers at UMass Medical School and the University of Queensland in Australia identifies a never-before-seen type of immune response in an animal already known for being unique: the koala bear. Koalas ...
Oct 10, 2019
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Oncology & Cancer
Chemistry nobel DNA research lays foundation for new ways to fight cancer
Our cells are up against a daily onslaught of damage to the DNA that encodes our genes. It takes constant effort to keep up with the DNA disrepair – and if our cells didn't bother to try to fix it, we might not survive. ...
Oct 9, 2015
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