Extra copies of a piece of DNA partly explain insensitivity to chemotherapy in germ cell cancer, a new study shows. According to research leader Prof. Dr. Leendert Looijenga, "In the future, our findings could help pick out ...
Apr 20, 2022
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Inheriting a normal and intact number of chromosomes in germ cells, egg and sperm, is essential for the preservation of all species. With increasing age, the risk of the egg cell not inheriting the normal set of chromosomes ...
Feb 04, 2022
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Around half of the genome is made up of transposable elements or 'jumping genes' that derive from ancient viral integrations. They persist in various states of decay like an old fashioned 'pull your own' junkyard where parts ...
Sometimes the best way to understand a biological process is to disrupt the normal process and analyze the result.
Nov 17, 2021
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For species that rely on sexual reproduction, including mice and men, offspring can only happen if sperm from the male fertilize eggs from the female. Even artificial fertilization techniques depend on donors for both of ...
Sep 07, 2021
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Drugs targeting the gene MAGEA3 may help block the growth of hepatocellular carcinoma (HCC), the most common type of primary liver cancer and one of the leading causes of cancer deaths in the country. That's one conclusion ...
Jun 24, 2021
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Testicular cancer is the most common type of cancer to affect men between the ages of 15 and 49, and around 95% of these cases are caused by testicular germ cell tumors. Although testicular germ cell tumors typically manifest ...
Apr 28, 2021
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In 2012, proud dad Ramjit Raghav made global headlines when he became a father at the age of 96. He had beaten the record for the world's oldest dad—a record he'd set himself, two years earlier, at the age of 94.
Mar 04, 2021
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People who live through traumatic experiences in childhood often suffer long-lasting consequences that affect their mental and physical health. But moreover, their children and grandchildren can also be impacted as well. ...
Oct 15, 2020
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Recently published work from Carnegie's Allan Spradling and Wanbao Niu revealed in unprecedented detail the genetic instructions immature egg cells go through step by step as they mature into functionality. Their findings ...
Oct 08, 2020
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Germ cells are progenitors of the gametes. These singled-out cells move through the gut to the developing gonads and undergo mitotic proliferation followed by meiosis and differentiation into either eggs or sperm (mature gametes). Plants do not have a germ line set aside in early development. Instead germ cells can come from somatic cells in the adult floral meristem.
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