Diseases, Conditions, Syndromes

COVID-19 cytokine storms may prevent a durable immune response

Shiv Pillai, MD, Ph.D., investigator in the Ragon Institute of MGH, MIT and Harvard and professor at Harvard Medical School (HMS), recently published a paper in Cell showing that high levels of some cytokines seen in COVID-19 ...

HIV & AIDS

New HIV vaccine strategy 'pumps' the immune system

A new HIV vaccine delivery strategy appears to enhance the protective immune response in a preclinical model. Scientists at the La Jolla Institute for Immunology (LJI) have discovered that delivering an HIV vaccine in small ...

Immunology

Finding what fuels the 'runaway train' of autoimmune disease

A newly-unveiled discovery, which has been four years in the making, has the potential to change the way we look at autoimmune diseases and understand how and why immune cells begin to attack different tissues in the body.

Diseases, Conditions, Syndromes

What makes an mRNA vaccine so effective against severe COVID-19?

The first two vaccines created with mRNA vaccine technology—the Pfizer/BioNTech and Moderna COVID-19 vaccines—are arguably two of the most effective COVID vaccines developed to date. In clinical trials, both were more ...

Diseases, Conditions, Syndromes

Antibodies improve in quality for months after COVID-19 vaccination

For at least six months after COVID-19 vaccination, antibodies produced by immune cells become steadily more formidable and more precisely targeted against the virus that causes COVID-19, according to a study of the antibody ...

Medical research

When the body's B cell training grounds stay open after hours

If B cells are the munitions factories of the immune system, manufacturing antibodies to neutralize harmful pathogens, then the tiny biological structures known as germinal centers are its weapons-development facilities. ...

Medical research

New clues about why a universal flu vaccine is so elusive

Every year, we're reminded to return to the pharmacy for a flu shot. Why can't we have a flu vaccine that offers long-term protection, like those for measles or polio? That's because the influenza virus continuously evolves, ...

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