Medical research

Shape-shifting fat cells fuel breast cancer growth

Fat cells, or adipocytes, that grow in close proximity to breast cancers can shift into other cell types that promote tumor growth, a new study by UT Southwestern researchers suggests. The findings, published in Cell Reports, ...

Oncology & Cancer

Researchers identify an Achilles' heel in neuroblastoma

Neuroblastoma, a childhood cancer that develops from neural cells on the adrenal glands, accounts for 15% of childhood cancer deaths. Almost half of children with high-risk neuroblastoma harbor extra copies of the gene MYCN ...

Oncology & Cancer

New understanding of how faulty metabolism triggers adrenal cancer

Researchers have deciphered a signaling cascade through which inborn errors in metabolism provoke deadly neuroendocrine tumors in the adrenal glands. This discovery explains how impaired metabolism due to mutations in a key ...

Ophthalmology

Nothing to cry about: The development of tear duct organoids

Advancements in cell culture methods have allowed for the development of organoids—stem cell-derived mini-organs that mimic the tissue organization of our body. Now, researchers in Japan have developed a new organoid system ...

Obstetrics & gynaecology

Hormone found to regulate mothers' behavior

University of Otago researchers have discovered a new function for the hormone prolactin—it limits a new mom's investment in aggressive behavior and instead focuses them on interacting with their babies.

Immunology

Why don't adrenal gland metastases respond to immunotherapy?

Recent advances in immunotherapy have allowed doctors at the University of Colorado Cancer Center to more effectively treat melanomas that spread to other parts of the body. Immunotherapy drugs such as checkpoint inhibitors, ...

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