Medical research

Crying human tear glands grown in the lab

Researchers from the lab of Hans Clevers (Hubrecht Institute) and the UMC Utrecht used organoid technology to grow miniature human tear glands that actually cry. The organoids serve as a model to study how certain cells in ...

Diseases, Conditions, Syndromes

First lab-grown mini-thyroids use patients' own tissue

Hormones produced by the thyroid gland are essential regulators of organ function. The absence of these hormones either through thyroid dysfunction due to, for example, irradiation, thyroid cancer or autoimmune disease or ...

Oncology & Cancer

New drug targets for childhood cancer neuroblastoma identified

The largest single cell study to date of the childhood cancer, neuroblastoma, has answered important questions about the genesis of the disease. The researchers from the Wellcome Sanger Institute, Great Ormond Street Hospital ...

Medical research

Stress on every cell: Mapping the stress axis in detail

Chronic stress could be the prevailing condition of our time. In the short term, our jaws or stomachs may clench; in the long term, stress can lead to metabolic disease and speed up diseases of aging, as well as leading to ...

Genetics

Scientists map genes controlling immune system 'brakes'

Unlike most T cells, which launch immune responses against foreign molecules, regulatory T cells are the peacekeepers of the human immune system, damping down inflammatory reactions when they're not needed. Now, researchers ...

Diseases, Conditions, Syndromes

Coronavirus damages the endocrine system

People with endocrine disorders may see their condition worsen as a result of COVID-19, according to a new review published in the Journal of the Endocrine Society.

Medical research

A novel radioisotope therapy for children with neuroblastoma

Researchers from Kanazawa University retrospectively analyzed children with refractory or relapsed high-risk neuroblastoma who were treated with high-dose 131I-metaiodobenzylguanidine at Kanazawa University Hospital. They ...

Medical research

Identification of a determining factor in luminal cancer cells

The Translational Control of Cell Cycle and Differentiation Lab at IRB Barcelona, led by ICREA researcher Raúl Méndez, has published a study in the journal Science Advances that has identified a key factor in the development ...

Medical research

Perspiration problems? No sweat!

Solving sweat-related concerns that occur in daily life, such as hyperhidrosis and sweat smell, can improve people's quality of life. Now, researchers from Osaka University, in collaboration with Mandom Corporation, have ...

Medical research

New discovery explains how the prostate gland regenerates itself

The standard treatment for men with advanced prostate cancer is androgen-deprivation therapy. Androgens are hormones that fuel prostate cell growth; removing them with either drugs or surgery causes the prostate gland to ...

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