Glutamate is the primary excitatory neurotransmitter of the central nervous system, in excess it causes cells to become overexcited, which contributes to neuron death in neurodegenerative disease. Now, a study of flies led ...
Oct 5, 2017
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Vanderbilt University researchers have relieved symptoms of Rett syndrome in a mouse model with a small molecule that works like the dimmer switch in an electrical circuit.
Aug 23, 2017
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Columbia University Medical Center (CUMC) researchers have captured the first three-dimensional snapshots of the AMPA-subtype glutamate receptor in action. The receptor, which regulates most electrical signaling in the brain, ...
Jul 24, 2017
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A translational, multicenter study has unveiled the potential of D-serine—a dietary supplement—to improve the neuronal function of a patient with a mutation of the glutamate receptors associated to atypical Rett syndrome ...
Jul 4, 2017
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While most research on Alzheimer's disease (AD) has focused on early diagnosis and treatment, University at Buffalo scientists are studying genetic and epigenetic factors with the ultimate goal of restoring function to patients ...
Jun 27, 2017
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Major depressive disorder (MDD) impacts 15 million Americans and is the leading cause of disability, yet current treatments possess limited efficacy. Ketamine, which has been repurposed as a rapidly acting antidepressant, ...
Mar 17, 2017
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Experiments in mice by researchers at Johns Hopkins suggest that if the goal is to ease or extinguish fearful emotional memories like those associated with post-traumatic stress disorder, alcohol may make things worse, not ...
Jan 10, 2017
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For decades, scientists thought acetylcholine was the only neurotransmitter responsible for controlling how muscles and nerves are wired together during development.
Sep 19, 2016
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University of North Carolina researchers uncovered a cellular mechanism by which kappa opioid receptors (KOR) drive anxiety. These proteins inhibit the release of the neurotransmitter glutamate in a part of the brain that ...
Mar 17, 2016
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NMDA glutamate receptors, which function as receptors that bond with glutamates, are known to be deeply involved in animal memory and learning. In order for memories to be created inside the brain, these NMDA glutamate receptors ...
Feb 5, 2016
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