Scientists have used CRISPR-Cas9 gene editing to lessen some autism symptoms in mice with a form of fragile X syndrome, the most common known single-gene cause of autism spectrum disorder.
Jun 25, 2018
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231
Columbia University Medical Center (CUMC) researchers have captured the first three-dimensional snapshots of the AMPA-subtype glutamate receptor in action. The receptor, which regulates most electrical signaling in the brain, ...
Jul 24, 2017
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Strengthening and weakening the connections between neurons, known as synapses, is vital to the brain's development and everyday function. One way that neurons weaken their synapses is by swallowing up receptors on their ...
Jan 15, 2016
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MIT neuroscientists have discovered that the adult brain contains millions of "silent synapses"—immature connections between neurons that remain inactive until they're recruited to help form new memories.
Nov 30, 2022
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One of the most important molecules in the brain doesn't work quite the way scientists thought it did, according to new work by researchers at Columbia University Vagelos College of Physicians and Surgeons and Carnegie Mellon ...
Apr 20, 2022
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Brian Falkner said "We are our memories."
Apr 6, 2022
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417
Stressful experiences can lead to adaptive or detrimental behaviors. Understanding how stress can affect our brains can help understand basic brain function and is also essential to discerning causes and treatments for some ...
Feb 18, 2022
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Neurobiologists at Heidelberg University have discovered how a special receptor at neuronal junctions that normally activates a protective genetic program can lead to nerve cell death when located outside synapses. Their ...
Oct 8, 2020
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327
Glutamate is the messenger substance the brain uses to pass on excitatory signals. Receptors for this neurotransmitter are a promising target for drug development, as they are involved in many pathological processes. For ...
Oct 1, 2020
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Researchers at Tufts University School of Medicine and Tufts Graduate School of Biomedical Sciences have discovered neural mechanisms in mice specific to females that can shift estrogen from playing a protective role in glucose ...
Aug 6, 2020
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