Trim the sugar: New HIV vaccine design improves immune response

A new HIV vaccine from Scripps Research has shown a significantly improved ability to neutralize the virus in preclinical tests, and it will soon be studied in healthy people who volunteer to participate in clinical trials.

Alzheimer's disease & dementia

Sugar molecule in blood can predict Alzheimer's disease, suggests study

Early diagnosis and treatment of Alzheimer's disease requires reliable and cost-effective screening methods. Researchers at Karolinska Institutet in Sweden have now discovered that a type of sugar molecule in blood is associated ...

Diseases, Conditions, Syndromes

Antibody properties in plasma can predict COVID-19 severity

Alterations in the biochemical makeup of bulk plasma IgG, or Fc glycosylation, can predict COVID-19 disease severity and vaccine antibody response, according to a recent study by researchers at RUSH University and Northwestern. ...

Medical research

Sugar chains on cell surfaces direct cancer cells to die

A cytokine named TRAIL binds to TRAIL receptors and kills cancer cells, but not normal cells. Various anticancer drugs targeting TRAIL receptors have been developed and gained great attention as a promising cancer therapeutics, ...


Researchers link sugar-studded protein to Alzheimer's disease

In a bit of "reverse engineering" research using brain tissues from five people who died with Alzheimer's disease, Johns Hopkins Medicine researchers say they discovered that a special sugar molecule could play a key role ...

Obstetrics & gynaecology

Study finds potential predictor for perimenopause

A new study has found women 'age' significantly faster in the perimenopausal period, based on analysis of the IgG glycome. This finding indicates the potential of using the IgG glycome composition as an early predictor for ...

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