Diseases, Conditions, Syndromes

Vaccine candidate for gonorrhea shows preclinical effectiveness

A report in the journal mBio, published by the American Society for Microbiology, describes a prototype vaccine candidate for Neisseria gonorrhoeae, the bacterium that causes gonorrhea, a sexually transmitted infection that ...

Diseases, Conditions, Syndromes

Pay-it-forward model increases STD testing among gay men in China

Chinese gay men who were offered a free screening for gonorrhea and chlamydia and then asked to donate to the testing of another man were 48 percent more likely to get tested than men who were offered the standard of care. ...

Diseases, Conditions, Syndromes

Novel antibiotic shows promise in treatment of uncomplicated gonorrhea

An investigational oral antibiotic called zoliflodacin was well-tolerated and successfully cured most cases of uncomplicated gonorrhea when tested in a Phase 2 multicenter clinical trial, according to findings published today ...

Diseases, Conditions, Syndromes

Mouse models may not accurately mimic severity of gonorrhea infection

There is an urgent need to develop a vaccine to prevent gonorrhea infection due to rapidly increasing incidence and growing antibiotic resistance. BUSM researchers (in collaboration with University of Toronto researchers) ...

Diseases, Conditions, Syndromes

In US, sexuallly transmitted infections hit new highs

Sexually transmitted infections like chlamydia, gonorrhea and syphilis soared to new record highs in the United States last year, public health officials said Tuesday.

Diseases, Conditions, Syndromes

How did gonorrhea become a drug-resistant superbug?

The bacterium that causes the sexually transmitted disease gonorrhea is resistant to multiple standard antibiotics and now threatens to develop resistance against ceftriaxone, which is on the World Health Organization List ...

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Gonorrhea

Gonorrhea (also colloquially known as the clap) is a common sexually transmitted infection caused by the bacterium Neisseria gonorrhoeae. The usual symptoms in men are burning with urination and penile discharge. Women, on the other hand, are asymptomatic half the time or have vaginal discharge and pelvic pain. In both men and women if gonorrhea is left untreated, it may spread locally causing epididymitis or pelvic inflammatory disease or throughout the body, affecting joints and heart valves.

Treatment is commonly with ceftriaxone as antibiotic resistance has developed to many previously used medications.

In 2011, there were reports of some strains of gonorrhea showing resistance to ceftriaxone.

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