Inflammatory disorders

Native Hawaiians are more at risk for gout, study reveals

An analysis of nearly two decades of data has revealed that Native Hawaiian study participants had more than twice the risk of developing gout as older adults, relative to white participants. Black and Japanese participants ...

Diseases, Conditions, Syndromes

What do you know about rheumatic diseases?

September is Rheumatic Disease Awareness Month, which makes this a good time to learn about four common rheumatic diseases: Ankylosing spondylitis, gout, juvenile idiopathic arthritis and lupus.

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Gout

Gout (also known as podagra when it involves the big toe) is a medical condition usually characterized by recurrent attacks of acute inflammatory arthritis—a red, tender, hot, swollen joint. The metatarsal-phalangeal joint at the base of the big toe is the most commonly affected (approximately 50% of cases). However, it may also present as tophi, kidney stones, or urate nephropathy. It is caused by elevated levels of uric acid in the blood which crystallize and are deposited in joints, tendons, and surrounding tissues.

Diagnosis is confirmed clinically by the visualization of the characteristic crystals in joint fluid. Treatment with nonsteroidal anti-inflammatory drugs (NSAIDs), steroids, or colchicine improves symptoms. Once the acute attack has subsided, levels of uric acid are usually lowered via lifestyle changes, and in those with frequent attacks allopurinol or probenecid provide long-term prevention.

Gout has increased in frequency in recent decades affecting approximately one to two percent of the Western population at some point in their lives. The increase is believed to be due to increasing risk factors in the population, such as metabolic syndrome, longer life expectancy and changes in diet. Gout was historically known as "the disease of kings" or "rich man's disease".

This text uses material from Wikipedia, licensed under CC BY-SA