Arthritis & Rheumatism

Study identifies potential new target for treatment of gout

Researchers at Washington State University Health Sciences Spokane and elsewhere have identified a new therapeutic target for the treatment of gout, a common type of arthritis that causes episodes of painful and stiff joints.

Diseases, Conditions, Syndromes

Short-term probiotics regimen may help treat gout, kidney disease

New research suggests that an individualized probiotic therapy regimen may improve symptoms of gout, gout-related kidney disease and other signs of metabolic syndrome. The study will be presented today at the American Physiological ...

Arthritis & Rheumatism

Modifiable risk factors contribute to gout

Elevated urate in the blood (hyperuricemia) is a precursor of gout, which is the most common form of inflammatory arthritis worldwide. A study published in Arthritis & Rheumatology that included 14,624 U.S. adults found that ...

Medications

Are opioids being inappropriately prescribed to treat gout?

Although there are effective treatments for gout, the most common form of inflammatory arthritis, a new Arthritis Care & Research study found that opioids are commonly prescribed to patients with gout who seek treatment at ...

Arthritis & Rheumatism

Exposure to inorganic dust increases risk of gout in women by 27%

The results of a study presented today at the Annual European Congress of Rheumatology (EULAR 2019) demonstrate that occupational exposure to inorganic dust is a previously unknown risk factor for gout and also confirm known ...

Arthritis & Rheumatism

A new treatment for gout lowers the urinary acid level in the body

Gout is an inflammatory disease that can cause very painful attacks. The illness is also called podagral, or colloquially "The Captain's syndrome". It primarily affects men, particularly over 40 years of age. Symptoms of ...

Arthritis & Rheumatism

FDA: Gout drug uloric increases risk of death

(HealthDay)—The gout medicine Uloric (febuxostat) carries a higher risk of death than allopurinol, according to the U.S. Food and Drug Administration.

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Gout

Gout (also known as podagra when it involves the big toe) is a medical condition usually characterized by recurrent attacks of acute inflammatory arthritis—a red, tender, hot, swollen joint. The metatarsal-phalangeal joint at the base of the big toe is the most commonly affected (approximately 50% of cases). However, it may also present as tophi, kidney stones, or urate nephropathy. It is caused by elevated levels of uric acid in the blood which crystallize and are deposited in joints, tendons, and surrounding tissues.

Diagnosis is confirmed clinically by the visualization of the characteristic crystals in joint fluid. Treatment with nonsteroidal anti-inflammatory drugs (NSAIDs), steroids, or colchicine improves symptoms. Once the acute attack has subsided, levels of uric acid are usually lowered via lifestyle changes, and in those with frequent attacks allopurinol or probenecid provide long-term prevention.

Gout has increased in frequency in recent decades affecting approximately one to two percent of the Western population at some point in their lives. The increase is believed to be due to increasing risk factors in the population, such as metabolic syndrome, longer life expectancy and changes in diet. Gout was historically known as "the disease of kings" or "rich man's disease".

This text uses material from Wikipedia, licensed under CC BY-SA