Medical research

Scientists illuminate mechanism of common drug target

Roughly a third of all drugs approved by the U.S. Food and Drug Administration target a large family of biomolecules, known as G protein-coupled receptors (GPCRs), whose job is to trigger cellular responses to extracellular ...

Medical research

Geometry plays a role in GPCR transmembrane signaling

A recent study in The Journal of General Physiology characterizes the movement of rhodopsin, a GPCR and member of a large family of transmembrane receptors responsible for many cellular responses and involved in many human ...

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