Immunology

Study reframes understanding of graft-versus-host disease

New research challenges the prevailing hypothesis for how donor stem cell grafts cause graft-versus-host disease, or GVHD, and offers an alternative model that could guide development of novel therapies.

Immunology

Study uncovers mechanism behind primary graft dysfunction

Northwestern Medicine scientists have discovered the pathways through which autoantibodies—immune proteins that mistakenly attack a person's own body—leak out of blood vessels and cause primary graft dysfunction in some ...

Oncology & Cancer

Cell therapy could improve bone marrow transplant safety

UCLA researchers report a step forward in the development of an "off-the-shelf" cell therapy that could reduce the severity of graft-versus-host disease in people receiving donor bone marrow transplants for the treatment ...

Surgery

ACL reconstruction goes under the microscope

You don't have to be an avid sports fan to recognize the term "ACL injury." Damage to the anterior cruciate ligament (ACL)—a tendon in the knee—is prevalent even among amateur sports players, and treatment often requires ...

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