Assistant Professor Shunsuke Funakoshi, Associate Professor Yoshinori Yoshida, and their research team have identified Am80 as a molecule that activates the cell cycle in cardiomyocytes to enhance cardiac tissue graft production ...
Jul 14, 2023
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Clinicians have a new standard for graft-versus-host disease (GVHD) prevention after allogeneic hematopoietic stem cell transplantation, according to results from a phase III study published June 22 in the New England Journal ...
Jun 22, 2023
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New animal research is helping explain why at least five people have become HIV-free after receiving a stem cell transplant. The study's insights may bring scientists closer to developing what they hope will become a widespread ...
May 25, 2023
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Repairing severely damaged bones is a challenge—especially the long bones of the arms and legs. Now, UConn Health scientists describe a new method in the May 22 issue of the Proceedings of the National Academy of Sciences ...
May 24, 2023
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A bone marrow transplant can be a lifesaving treatment for people with relapsed blood cancers, but a potentially lethal complication known as graft-versus-host disease put limitations on this procedure. New research from ...
Mar 24, 2023
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A man who underwent a stem cell transplant to treat his cancer is showing "strong evidence" that the procedure also cured him of HIV—the latest in a handful of cases doctors have reported.
Feb 20, 2023
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The severity of immune-mediated intestinal diseases such as graft-versus-host disease (GVHD) or inflammatory bowel diseases is known to be associated with alterations in the gut microbiome, but what leads to such disruption ...
Feb 2, 2023
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If you've ever tried giftwrapping an odd-shaped present like a teddy bear, you can appreciate the challenge that surgeons face when grafting artificial skin onto an injured body part. Like wrapping paper, engineered skin ...
Jan 31, 2023
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New research challenges the prevailing hypothesis for how donor stem cell grafts cause graft-versus-host disease, or GVHD, and offers an alternative model that could guide development of novel therapies.
Jan 30, 2023
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Organ damage occurs in up to 70% of patients in the first few months following stem cell transplant. The precise reasons for this potentially life-threatening reaction have long been the subject of scientific research.
Oct 13, 2022
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