Surgery

Bioengineered skin grafts that fit like gloves

If you've ever tried giftwrapping an odd-shaped present like a teddy bear, you can appreciate the challenge that surgeons face when grafting artificial skin onto an injured body part. Like wrapping paper, engineered skin ...

Cardiology

Vascular grafts: Technology success or technology failure?

Blood vessel replacements (vascular grafts) are used today for hemodialysis blood access, trauma repair and cardiovascular reconstruction. The first synthetic vascular grafts (blood vessel replacements) were developed just ...

Immunology

Study reframes understanding of graft-versus-host disease

New research challenges the prevailing hypothesis for how donor stem cell grafts cause graft-versus-host disease, or GVHD, and offers an alternative model that could guide development of novel therapies.

Immunology

Study uncovers mechanism behind primary graft dysfunction

Northwestern Medicine scientists have discovered the pathways through which autoantibodies—immune proteins that mistakenly attack a person's own body—leak out of blood vessels and cause primary graft dysfunction in some ...

Oncology & Cancer

Cell therapy could improve bone marrow transplant safety

UCLA researchers report a step forward in the development of an "off-the-shelf" cell therapy that could reduce the severity of graft-versus-host disease in people receiving donor bone marrow transplants for the treatment ...

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