Neuroscience

Smoking and alcohol: Double trouble for the brain?

Along with many other harmful health consequences, smoking tobacco causes chemical changes, oxidative stress and inflammation in the brain. Excessive alcohol use can have similar effects. Surprisingly, however, very few studies ...

Medications

Origin of resistance to lung-cancer drug discovered

Researchers at Kanazawa University report in Nature Communications that AXL, a protein belonging to the class of receptor tyrosine kinases, causes some lung cancer patients to have an intrinsic resistance to the drug osimertinib. ...

Alzheimer's disease & dementia

Insulin signaling failures in the brain linked to Alzheimer's disease

Scientists continue to find evidence linking Type 2 diabetes with Alzheimer's disease, the most common form of dementia and the seventh leading cause of death in the United States. However, little is understood about the ...

Medications

BDNF–VEGF interplay key to rapid antidepressant actions

A study by researchers at Yale University reveals a complex interplay of two different growth factors in the rapid and long-lasting antidepressant effects of ketamine. The study, published in Biological Psychiatry, reports ...

Medical research

Enzyme that breaks down amino acids may promote aging

Permanently arrested cell growth is known as "cellular senescence", and the accumulation of senescent cells may be one cause of aging in our bodies. Japanese researchers have discovered that a certain enzyme in our bodies ...

Neuroscience

Gene therapy promotes nerve regeneration

Researchers from the Netherlands Institute for Neuroscience (NIN) and the Leiden University Medical Center (LUMC) have shown that treatment using gene therapy leads to a faster recovery after nerve damage. By combining a ...

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