Oncology & Cancer

Enzyme checkpoint identified in tumor-associated macrophages

A study by a scientific team from the University of Vienna and the MedUni Vienna, recently published in Cellular & Molecular Immunology, shows that the enzyme phosphoglycerate dehydrogenase (PHGDH) acts as a metabolic checkpoint ...

Oncology & Cancer

Immune cell receptor provides promising immunotherapy target

Drugs that target a receptor on immune cells called activin receptor 1C may combat tumor-induced immune suppression and help patients' immune systems fight back against cancer, according to a study by investigators at the ...

Surgery

Special gel could help in surgery after pelvic organ prolapse

Of women who have had surgery for pelvic organ prolapse, 20% require surgery again. This is usually due to suboptimal wound healing after surgery. The synthetic PIC gel (discovered at Radboud University) might help improve ...

Oncology & Cancer

Re-exposing a cancer protein to enhance immunotherapy

Successful immunotherapy for cancer involves activating a person's own T cells to identify telltale proteins called antigens on the surface of a tumor and attack it. But some tumors have a trick: They hide themselves from ...

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