Organ damage occurs in up to 70% of patients in the first few months following stem cell transplant. The precise reasons for this potentially life-threatening reaction have long been the subject of scientific research.
Oct 13, 2022
0
40
Researchers at The University of Texas MD Anderson Cancer Center have identified a specific gut bacterium involved in the progression of graft-versus-host disease (GVHD) after antibiotic treatment of allogeneic hematopoietic ...
Sep 29, 2022
0
30
MUSC Hollings Cancer Center researcher Yongxia Wu, Ph.D., identified a new target molecule in the fight against graft-versus-host disease (GVHD). Bone marrow transplant, a treatment for certain blood cancers, is accompanied ...
Feb 12, 2021
0
24
A recent report published in Science Translational Medicine by MUSC Hollings Cancer Center investigator Sophie Paczesny, M.D., Ph.D., sheds light on immune cell biomarkers that may reveal which patients are most at risk for ...
Oct 7, 2020
0
40
Allogenic hematopoietic stem cell transplantation (HSCT) is a procedure that infuses a donor's healthy blood-forming stem cells into a recipient as part of a potentially curative therapy for cancer. While this therapy can ...
Aug 28, 2020
0
106
In a new study published in Science Translational Medicine, Robert Levy, Ph.D., along with graduate student and first author Cameron Bader and colleagues, have shown that inhibiting the STING protein pathway could protect ...
Jul 15, 2020
0
76
Mutations in white blood cells can contribute to abnormal immune profile after hematopoietic stem cell transplantation.
May 7, 2020
0
53
A protein that protects people with inflammatory bowel disease has quite a different effect in graft-vs.-host disease, a common and challenging side effect of bone marrow transplants.
Mar 22, 2019
0
38
Bone marrow transplant (BMT) offers patients with leukemia and lymphoma a potentially curative treatment. Bone marrow from the donor contains healthy immune cells (T cells and B cells), whose mission is to protect the body ...
Jan 25, 2019
0
313
Stem cell transplants can cure patients with high-risk leukemia or lymphoma. Graft-versus-host disease (GVHD) is a potentially life-threatening side effect that occurs when the donor's immune cells attack the recipient's ...
Feb 5, 2018
0
34
