Oncology & Cancer

How a leukemia hijacks the genes needed by blood stem cells

As a child, Lynn Aureli didn't know that a particular genetic change contributed to her acute myeloid leukemia (AML)—an alteration that eventually would help explain the cancer's lack of response to chemotherapy. Nor was ...

Oncology & Cancer

CAR T cell therapy may eliminate tumor cells missed by surgery

CAR T cell therapy, an approach which reprograms patients' own immune cells to attack their blood cancers, may enhance the effectiveness of surgery for solid tumors, according to a preclinical study from researchers in the ...

Medical research

Looking for an early sign of LATE: New insights into the pathology

Limbic predominate age-related TDP-43 encephalopathy or LATE is a recently recognized form of dementia that affects memory, thinking and social skills. It mimics Alzheimer's disease or AD (and sometimes co-exists with it), ...

Cardiology

Examining how poor diet damages blood vessels

Over the course of the last several decades, the rate of obesity has progressively increased and is now one of the leading causes of death worldwide—650 million adults are classified as obese. The World Health Organization ...

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