Neuroscience

Team discovers second stem cell type in mouse brain

In the brain of adult mammals, neural stem cells ensure that new nerve cells (neurons), are constantly formed. This process, known as adult neurogenesis, helps mice maintain their sense of smell. A research team led by Dr. ...

Oncology & Cancer

Exploring the biology of 'double positive' T cells

The molecular markers CD4 and CD8—defining helper T cells and killer T cells, respectively—were once considered mutually exclusive. But "double positive" CD4+-CD8+ T cells have lately been discovered in people in various ...

Immunology

How the body identifies helpful bacteria

Trillions of bacteria and other microbes thrive in our gut microbiomes, and over the last decade, scientists have become increasingly aware of the vital role that they play in creating a healthy gastrointestinal environment. ...

Immunology

Study identifies key player in T cell 'education'

Vanderbilt researchers have identified a protein that is key to the "education" of immature T cells in the thymus. The findings, reported in the Journal of Experimental Medicine, could inform therapeutic strategies for enhancing ...

Diseases, Conditions, Syndromes

COVID-19: New energy for flagging immune cells

In severe COVID-19 patients, metabolism produces insufficient amounts of certain energy-rich compounds called ketone bodies. However, these energy carriers are needed by two important cell types in the immune system in order ...

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