Medical research

Bacterial infection stresses hematopoietic stem cells

It has been thought that only immune cells would act as the line of defense during bacterial infection. However, recent research has revealed that hematopoietic stem cells, cells that create all other blood cells throughout ...

Medical research

Using barcodes to trace cell development

How do the multiple different cell types in the blood develop? Scientists have been pursuing this question for a long time. According to the classical model, different developmental lines branch out like in a tree. The tree ...

Medical research

Innate reaction of hematopoietic stem cells to severe infections

Researchers at the University of Zurich have shown for the first time that hematopoietic stem cells detect infectious agents themselves and begin to divide—that is, without signals from growth factors. This direct production ...

Immunology

How ancestry shapes our immune cells

Virtually the entire population of sub-Saharan Africa, and some 70% of African Americans, carry a gene variant (allele) which results in a trait referred to as Duffy-negative. It has long been known that carriers of this ...

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