Genetics

A new CRISPR-engineered cancer model to test therapeutics

One major challenge in cancer research is developing robust pre-clinical models for new therapies, ones that will accurately reflect a human response to a novel compound. All too often, a potential treatment that initially ...

Oncology & Cancer

Good survival for HSCT-treated thalassemia patients

(HealthDay)—Patients with thalassemia treated with hematopoietic stem cell transplantation (HSCT) have 30-year survival that is similar to that of conventionally treated (CT) patients, according to a study published online ...

Medical research

Bacterial infection stresses hematopoietic stem cells

It has been thought that only immune cells would act as the line of defense during bacterial infection. However, recent research has revealed that hematopoietic stem cells, cells that create all other blood cells throughout ...

Medical research

Using barcodes to trace cell development

How do the multiple different cell types in the blood develop? Scientists have been pursuing this question for a long time. According to the classical model, different developmental lines branch out like in a tree. The tree ...

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