Fibrosis is the thickening of various tissues caused by the deposition of fibrillar extracellular matrix (ECM) in tissues and organs as part of the body's wound healing response to various forms of damage. When accompanied ...
Jul 11, 2022
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More than 300,000 people suffer a heart attack in Germany every year. In this case, the heart muscle is no longer supplied with sufficient blood and oxygen, and part of the heart muscle tissue dies and becomes scarred. The ...
Jun 17, 2022
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UCLA scientists and colleagues have created a first-of-its-kind roadmap that traces each step in the development of blood stem cells in the human embryo, providing scientists with a blueprint for producing fully functional ...
Apr 13, 2022
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For patients with acute lymphoblastic leukemia with resistance to C19 CAR T-cell therapy, resistance mechanisms that can be detected prior to treatment have been identified, according to a study presented at the annual meeting ...
Apr 12, 2022
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New research has begun to unravel the mystery of why a particular form of leukemia in infants has defied efforts to improve outcomes, despite significant improvements in treating older children. Scientists from the Wellcome ...
Mar 14, 2022
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Researchers from The University of Texas MD Anderson Cancer Center discovered that treatment resistance in patients with myelodysplastic syndromes (MDS) is caused by two distinct classes of stem cells and identified possible ...
Mar 3, 2022
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Hematopoietic stem cells (HSCs) have the capacity to both self-renew and differentiate into all mature blood cell types, making them promising treatments for a variety of diseases. However, the mechanisms involved in engraftment—when ...
Mar 1, 2022
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A novel gene therapy promoted transfusion independence in more than 90 percent of adult and pediatric patients with transfusion-dependent beta-thalassemia, according to a recent clinical trial published in the New England ...
Feb 4, 2022
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Two recent discoveries by stem cell scientists at Cedars-Sinai may help make cancer treatment more efficient and shorten the time it takes for people to recover from radiation and chemotherapy.
Jan 25, 2022
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Over the past three decades, efforts to improve the results of standard treatment for patients with severe aplastic anemia have been largely unsuccessful. The phase III RACE trial, sponsored by the European Society for Blood ...
Jan 5, 2022
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