Diseases, Conditions, Syndromes

Hepatitis B: 'Sleep timer' for immune cells discovered

In chronic hepatitis B, the liver contains immune cells that could destroy hepatitis B virus infected cells but are inactive. A team from the Technical University of Munich (TUM) has discovered that cells in blood vessels ...

Medications

What is PrEP? Will it stop me getting HIV?

HIV prevention was allocated A$43.9 million over three years in this week's federal budget. Some $26m of this is for "PrEP" for people without access to Medicare.

Genetics

Researchers may have found an Achilles heel for Hepatitis B

Tiny, dangerous, and easily transmitted hepatitis B virus (HBV) chronically affects about 296 million people and kills about 1 million every year. This stealthy virus invades the liver and remains largely asymptomatic until ...

Diseases, Conditions, Syndromes

Hepatitis viruses kill 3,500 people a day: WHO

More than 3,500 people die from hepatitis viruses every day and the global toll is rising, the World Health Organization warned on Tuesday, calling for swift action to fight the second-largest infectious killer.

Diseases, Conditions, Syndromes

Hepatitis B vaccine: What to know to protect yourself

Hepatitis is inflammation in the liver caused by specific viruses. The hepatitis viruses are referred to as types A, B, C, D and E. All types affect the liver, but they differ in illness severity and prevention options.

Oncology & Cancer

Discovery points to new approach to treating liver cancer

A breakthrough in the understanding of the relationship between a naturally occurring enzyme and the liver cancer drug sorafenib could improve the effectiveness of the drug, which currently prolongs the life of liver cancer ...

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Hepatitis B

Hepatitis B is a disease caused by HBV hepatitis B virus which infects the liver of hominoidae, including humans, and causes an inflammation called hepatitis. Originally known as "serum hepatitis", the disease has caused epidemics in parts of Asia and Africa, and it is endemic in China. About a third of the world's population, more than 2 billion people, have been infected with the hepatitis B virus. This includes 350 million chronic carriers of the virus. Transmission of hepatitis B virus results from exposure to infectious blood or body fluids containing blood.

The acute illness causes liver inflammation, vomiting, jaundice and—rarely—death. Chronic hepatitis B may eventually cause liver cirrhosis and liver cancer—a fatal disease with very poor response to current chemotherapy. The infection is preventable by vaccination.

Hepatitis B virus is an hepadnavirus—hepa from hepatotrophic and dna because it is a DNA virus—and it has a circular genome composed of partially double-stranded DNA. The viruses replicate through an RNA intermediate form by reverse transcription, and in this respect they are similar to retroviruses. Although replication takes place in the liver, the virus spreads to the blood where virus-specific proteins and their corresponding antibodies are found in infected people. Blood tests for these proteins and antibodies are used to diagnose the infection.

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