Immunology

Reviewing new challenges and opportunities for hepatitis B cures

Hepatitis B virus (HBV) is a significant public health problem, with over 296 million people chronically infected worldwide. Despite the availability of a safe and effective vaccine for over 40 years, HBV remains a leading ...

Diseases, Conditions, Syndromes

New standards to quantify hepatitis B virus reservoirs in liver cells

Approximately 300 million people are chronically infected with the hepatitis B virus (HBV), which can cause liver cirrhosis or cancer. Consequently, there is an urgent need for the development of HBV curative therapies. Due ...

Diseases, Conditions, Syndromes

Designer drugs to inhibit hepatitis A virus

Structure-based drug design revealed that a compound previously investigated for the treatment of head-and-neck cancer could function as a lead compound for the development of drugs to treat hepatitis A virus infection, according ...

Medications

Glecaprevir and pibrentasvir aid HCV-positive kidney transplants

(HealthDay)—By treating or preventing infection, glecaprevir and pibrentasvir (G/P) regimens are promising for increasing access to the transplantation of kidneys from hepatitis C virus (HCV)-positive donors to HCV-negative ...

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