Liver cancer is the third leading cause of cancer death and the sixth most common cancer type worldwide. Major risk factors include environmental and metabolic stressors, such as obesity, viral hepatitis and steatohepatitis ...
Apr 12, 2023
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A gene expression-based screening assay using chimeric mice with humanized hepatocytes revealed that letrozole has a modifying effect on fibrosis-related gene expression in the hepatocytes, including YAP, CTGF, TGF-β, and ...
Nov 8, 2022
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A study led by Texas A&M AgriLife Research provides compelling evidence of the important role of hepatocyte adenosine kinase in the progression of nonalcoholic fatty liver disease (NAFLD). The study, "Hepatocyte Adenosine ...
Oct 5, 2022
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The Ebola virus was first identified in 1976 near the Ebola River in the Democratic Republic of the Congo. Since then, there have been periodic outbreaks of Ebola Virus Disease (EVD), mostly in Africa, resulting in 13,700 ...
Sep 8, 2022
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Dr. Shui Guanghou's team from the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences has recently demonstrated that Ceramide synthases 2 (CerS2) plays a critical role in maintaining hepatic ...
Feb 15, 2022
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Non-alcoholic fatty liver disease is the most common liver disorder worldwide and is present in approximately 25 percent of the world's population. Over 90 percent of obese, 60 percent of diabetic, and up to 20 percent of ...
Jul 13, 2021
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New research presented at the ESCMID Conference on Coronavirus Diseases (ECCVID, online 23-25 September) suggests that the higher risk of poor COVID-19 outcomes in men could be explained by differences in circulating proteins ...
Sep 25, 2020
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Hepatocytes—the chief functional cells of the liver—are natural regenerators, and the lymph nodes serve as a nurturing place where they can multiply. In a new study published online and appearing in a coming issue of ...
Aug 24, 2020
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The results of a clinical trial released today in STEM CELLS Translational Medicine demonstrate how a topical solution made up of stem cells leads to the regrowth of hair for people with a common type of baldness.
May 19, 2020
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Isolated human hepatocytes are essential tools in preclinical and clinical liver research, but cell quality is highly variable. Now, researchers from Uppsala University have devised a simple protocol that improves hepatocyte ...
Dec 21, 2018
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