Oncology & Cancer

Metabolic enzyme promotes neuroblastoma aggressiveness

High-risk neuroblastoma is an aggressive childhood cancer with poor treatment outcomes. Despite intensive chemotherapy and radiotherapy, less than 50 percent of these children survive for five years. While the genetics of ...

Oncology & Cancer

Anti-inflammatory strategy stops aggressive childhood cancer

Researchers at Karolinska Institutet and Karolinska University Hospital have discovered that an anti-inflammatory drug candidate inhibiting the prostaglandin E2 producing enzyme mPGES-1 in the tumour stroma reduces tumour ...

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