St. Jude Children's Research Hospital scientists have mapped the effects of aberrant biological machinery that drives a deadly brain cancer called diffuse intrinsic pontine glioma (DIPG). The research included development ...
Dec 28, 2018
0
82
In defining the cellular context of diffuse midline gliomas, researchers find the cells fueling their growth and suggest a potential approach to treating them: forcing their cells to be more mature.
Apr 20, 2018
0
86
The prognosis for all children diagnosed with an aggressive brain tumor known as diffuse intrinsic pontine glioma (DIPG) and similar tumors has been mostly the same: dismal.
Jan 17, 2018
0
28
St. Jude Children's Research Hospital biologists have used engineered yeast cells to discover how a mutation that is frequently found in pediatric brain tumor high-grade glioma triggers a cascade of genomic malfunctions.
Jul 18, 2017
0
4
A study published in Molecular Cancer Research reveals that a tumor suppressor gene p16 is turned off by a histone mutation (H3.3K27M), which is found in up to 70 percent of childhood brain tumors called diffuse intrinsic ...
Jun 6, 2017
0
167
A single defect in a gene that codes for a histone—a "spool" that wraps idle DNA—is linked to pediatric cancers in a study published today in the journal Science.
May 12, 2016
0
31
(Medical Xpress) -- Three research teams have published papers in Nature, that together offer evidence suggesting that isocitrate dehydrogenase (IDH) enzyme mutations may play a role in altering activity that could have an ...
