Lung fibrosis is a debilitating disease affecting nearly 250,000 people in the U.S. alone with 50,000 new cases reported each year. There is currently no cure and limited available treatment options, underscoring the pressing ...
Sep 26, 2023
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Using brain tumor samples collected from children in the United States and Europe, an international team of scientists found that the drug panobinostat and similar gene regulating drugs may be effective at treating diffuse ...
May 4, 2015
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Research led by Peter Mac and published in Cancer Discovery has found a new combination therapy for acute myeloid leukemia (AML) that shows greater potency in a preclinical study than either drug used alone.
Jun 1, 2022
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The complex process regulating gene expression is often compared to following a recipe. Miss a genetic ingredient, or add it in the wrong order, and you could have a disaster on your hands.
Dec 15, 2016
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In defining the cellular context of diffuse midline gliomas, researchers find the cells fueling their growth and suggest a potential approach to treating them: forcing their cells to be more mature.
Apr 20, 2018
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Although certain genetic variants increase the risk of Alzheimer's disease (AD), age is the strongest known risk factor. But the way in which molecular processes of aging predispose people to AD, or become impaired in AD ...
Mar 5, 2018
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EPFL scientists have discovered how an anti-cancer drug could be repurposed to improve memory. It does so by supporting the cell's ability to read the very genes that are important for learning. The epigenetic mechanism of ...
Jun 13, 2022
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Data from the U.S. indicate that between 5 to 10 percent of mothers consume psychostimulants (such as amphetamine, cocaine or methamphetamine) during pregnancy. Apart from the negative impacts on the developing brain, many ...
Nov 21, 2019
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Researchers led by Azusa Inoue at the RIKEN Center for Integrative Medical Sciences (IMS) in Japan have discovered a gene responsible for prenatal death when critical transgenerational instructions are missing from egg cells. ...
Apr 27, 2022
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(Medical Xpress)—DNA is often called the blueprint of life, but the four-letter combinations that make up the genetic code are just part of the story. Built upon the DNA lies additional epigenetic information in the form ...
Jun 11, 2013
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