Researchers from the University of Oulu and Harvard University have found a previously unknown mechanism by which cells in the body sense oxygen. Lack of oxygen had a direct influence on the functioning of genes, and prevents ...
Mar 20, 2019
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A study published in Nature Communications found that an inhibitor of an enzyme called ACVR1 slows tumor growth and increases survival in an animal model of diffuse intrinsic pontine glioma (DIPG) - the most deadly brain ...
Mar 4, 2019
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With an estimated 1.6 million people in the U.S. dealing with inflammatory bowel disease (IBD), physicians can have a hard time telling which newly diagnosed patients have a high risk of severe inflammation or what therapies ...
Sep 20, 2018
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Nothobranchius furzeri, the African killifish, is the perfect model organism for research into aging processes because of its short lifespan, apparent signs of aging and a sequenced genome. Thus, researchers from the University ...
Jul 27, 2018
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Several childhood cancer cell types show features of immature neural cells, and there is evidence suggesting that these tumors may arise from neural crest stem cells that underwent abnormal changes during embryonic development. ...
Feb 20, 2018
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The prognosis for all children diagnosed with an aggressive brain tumor known as diffuse intrinsic pontine glioma (DIPG) and similar tumors has been mostly the same: dismal.
Jan 17, 2018
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Around 2.5 million people are affected by the autoimmune disease multiple sclerosis (MS), the most common central nervous system disease among young adults. There are around 12,500 MS sufferers in Austria and 400 new cases ...
Oct 17, 2017
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Researchers at Nanjing University and their collaborators have found that NatD, which mediates N-alpha-terminal acetylation (Nt-acetylation) of histone H4, promotes lung cancer progression by preventing histone H4 serine ...
Oct 13, 2017
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St. Jude Children's Research Hospital biologists have used engineered yeast cells to discover how a mutation that is frequently found in pediatric brain tumor high-grade glioma triggers a cascade of genomic malfunctions.
Jul 18, 2017
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A study published in Molecular Cancer Research reveals that a tumor suppressor gene p16 is turned off by a histone mutation (H3.3K27M), which is found in up to 70 percent of childhood brain tumors called diffuse intrinsic ...
Jun 6, 2017
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