Immunology

Cracking the code for hookworm infestation

Hookworms infect nearly around 700 million people in the world, mostly in countries where sanitation is poor, and people often walk barefoot.

Diseases, Conditions, Syndromes

Hookworm infection may cause cognitive impairment earlier than thought

Evidence from the lab of Raffi Aroian, Ph.D., shows that short-term human hookworm infection, even at low levels, can cause rapid, acute and measurable cognitive impairments in spatial memory among a mammalian animal model. ...

Diseases, Conditions, Syndromes

Low-cost anti-hookworm drug boosts female farmers' physical fitness

Impoverished female farm workers infected with intestinal parasites known as hookworms saw significant improvements in physical fitness when they were treated with a low-cost deworming drug. The benefits were seen even in ...

Diseases, Conditions, Syndromes

Scientists identify potential drug target in blood-feeding hookworms

In hookworms that infect and feed on the blood of mice, scientists have discovered a key step in blood digestion that can be targeted to disrupt the parasite's development and survival. These findings, published in PLOS Pathogens ...

Diseases, Conditions, Syndromes

Fast test can monitor drug resistance in hookworms

More than 2 billion people around the world are infected with intestinal helminths, parasitic worms that can cause disease, complicate pregnancies, and stunt the growth of children. A number of drugs are currently used to ...

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