Immunology
Cracking the code for hookworm infestation
Hookworms infect nearly around 700 million people in the world, mostly in countries where sanitation is poor, and people often walk barefoot.
Feb 12, 2020
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News tagged with hookworm
Diseases, Conditions, Syndromes
Scientists identify potential drug target in blood-feeding hookworms
In hookworms that infect and feed on the blood of mice, scientists have discovered a key step in blood digestion that can be targeted to disrupt the parasite's development and survival. These findings, published in PLOS Pathogens ...
Mar 22, 2018
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Health
Albendazole cuts enteric parasite prevalence in refugees
(HealthDay) -- The administration of a single 600-mg dose of albendazole to United States-bound refugees prior to departure from Africa and Southeast Asia reduces the prevalence of intestinal nematodes, according to a study ...
Apr 19, 2012
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Diseases, Conditions, Syndromes
Infecting healthy adults with hookworm is the next step toward eradicating the infection
When Anna Markowitz learned that George Washington University researchers were looking for healthy volunteers to infect with bloodthirsty hookworms, her decision was resolute.
Jul 7, 2015
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Diseases, Conditions, Syndromes
New drug prospect offers hope against hookworm infections
A drug candidate that is nearing clinical trials against a Latin American parasite is showing additional promise as a cure for hookworm, one of the most widespread and insidious parasites afflicting developing nations, according ...
Jul 3, 2012
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Diseases, Conditions, Syndromes
Prior hookworm infection could offer protection from severe COVID-19 symptoms
Prior infection by a parasitic hookworm has been shown to protect mice from severe SARS-CoV-2 disease, offering a potential explanation as to why certain human populations seemed to fare better during the height of the COVID-19 ...
Aug 14, 2023
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Medications
Clinical trial of human hookworm vaccine begins at Children's National Medical Center
Today, the Sabin Vaccine Institute, in partnership with the George Washington University and the Children's National Medical Center, began vaccinating participants for a Phase 1 clinical trial of a novel human hookworm vaccine. ...
Jun 13, 2012
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Medications
Clinical trials for first-ever human hookworm vaccine advance
The Sabin Vaccine Institute (Sabin) today announced the start of Part II of its Phase I clinical trial of the Na-GST-1 vaccine candidate, marking another major milestone in the progress toward developing a human hookworm ...
Nov 5, 2012
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Medications
Discovering new uses for old drugs
With the cost of putting a single new drug on the pharmacy shelves topping a staggering $1 billion, scientists are reporting development of a way to determine if an already-approved drug might be used to treat a different ...
Aug 1, 2012
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Diseases, Conditions, Syndromes
Study links disease, poverty and biodiversity
Poverty and disease often come together. That much is well understood. But how much does poverty foster disease? Or, how much can disease perpetuate poverty? And what's the role of nature, given that so many infectious diseases ...
Dec 28, 2012
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