Diseases, Conditions, Syndromes

Deconstructing the mechanics of bone marrow disease

Fibrosis is the thickening of various tissues caused by the deposition of fibrillar extracellular matrix (ECM) in tissues and organs as part of the body's wound healing response to various forms of damage. When accompanied ...

Oncology & Cancer

New method predicts childhood hyperdiploid B-ALL relapse risk

An international research team coordinated by Dr. Oscar Molina and Dr. Pablo Menéndez, from the Josep Carreras Leukaemia Research Institute, identifies chromosomal abnormalities associated with relapse in a frequent subset ...

Surgery

Iron-silicon alloy for implants that fix broken bones

Researchers from Skoltech and Sechenov University have 3D-printed and investigated the properties of samples of a porous iron-silicon alloy that the team considers promising for making implants for bone regeneration. The ...

Genetics

Change of temperature causes whole body reprogramming

Human beings, like most organisms, are constantly exposed to alternating colder or warmer temperatures. These environmental variations cause striking metabolic effects and require constant adaptations. While some of these ...

Medical research

Harnessing vaccine technology to heal bone

Although fractures normally heal, bone will not regenerate under several circumstances. When bone does not regenerate, major clinical problems could result, including amputation.

Medical research

Targeting TGF-β for treatment of osteogenesis imperfecta

A new study led by Baylor College of Medicine identifies an underlying mechanism of pathogenesis for osteogenesis imperfecta (OI) in human bone. The report, published in the Journal of Clinical Investigation, also shows the ...

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