Inflammation in the human body has been revealed to be managed through a unique, highly-organised shape of receptors that 'dance' across a cell surface, according to new research.
Jan 15, 2020
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Scientists have developed new drug compounds that thwart the pro-cancer activity of FOXM1, a transcription factor that regulates the activity of dozens of genes. The new compounds suppress tumor growth in human cells and ...
Jan 7, 2020
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For the first time, scientists identified and mapped the location of structural proteins in a pig ovary. Ongoing development of an "ink" with these proteins will be used for 3-D printing an artificial (or bio-prosthetic) ...
Jan 6, 2020
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One of the ways a cancer-causing gene works up enough power to turn a normal cell into a cancer cell is by copying itself over and over, like a Xerox machine. Scientists have long noticed that when cancer-causing genes do ...
Nov 21, 2019
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New research by Yale University scientists reports the discovery of "hyperhotspots" in the human genome, locations that are up to 170-times more sensitive to ultraviolet radiation (UV) from sunlight compared to the genome ...
Nov 14, 2019
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Using CRISPR/Cas9 knockout screens a multi-institutional research team systematically interrogated the essentiality of more than 10,000 forkhead box protein A1 (FOXA1) and CTCF binding sites in breast and prostate cancer ...
Nov 11, 2019
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A Michigan State University study led by a physiology graduate student in the College of Human Medicine has found that new drug combinations may prevent melanoma, an often deadly form of skin cancer, from becoming resistant ...
Nov 11, 2019
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A team of researchers affiliated with a large number of institutions in the U.S. has found that a subgroup of breast cancers have two PIK3CA mutations, and that such mutations occur on the same allele. In their paper published ...
A protein that breast, lung and other cancers use to promote their spread—or metastasis—to the brain, has been identified by a team led by Weill Cornell Medicine and New York-Presbyterian investigators. The protein, CEMIP, ...
Nov 4, 2019
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Viruses get a bad rap as potential cancer-causers, but at least one class of viruses that commonly live on human skin—so-called "low-risk" human papillomaviruses—appear to play an unwitting role in protecting us against ...
Oct 30, 2019
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