Scientists have uncovered that "gene misbehavior"—where genes are active when they were expected to be switched off—is a surprisingly common phenomenon in the healthy human population.
Jul 24, 2024
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As a species, humans like to think that we are fully in control of our decisions and behavior. But just below the surface, forces beyond our conscious control influence how we think and behave: our genes.
Jul 24, 2024
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A new study by scientists at deCODE Genetics shows that sequence variants drive the correlation between DNA methylation and gene expression. The same variants are linked to various diseases and other human traits.
Jul 24, 2024
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Scientists at the University of Sydney and Liverpool School of Tropical Medicine have made a remarkable discovery: a commonly-used blood thinner, heparin, can be repurposed as an inexpensive antidote for cobra venom.
Jul 17, 2024
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A new gene therapy treatment for Duchenne muscular dystrophy shows promise of not only arresting the decline of the muscles of those affected by this inherited genetic disease, but perhaps, in the future, repairing those ...
Jul 17, 2024
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In biomedical research involving human subjects, research ethics committees around the world have traditionally emphasized individual rights and protections for participants, including informed consent. The emerging field ...
Jul 12, 2024
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Adeno-associated virus (AAV)-based viral vectors used in human gene therapy can trigger innate immune pathways, leading to the initiation of adaptive immune responses. A new review article published in the journal Human Gene ...
Jul 10, 2024
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Researchers at the Francis Crick Institute have mapped all the possible outcomes of changes to a tumor-suppressing gene called VHL, the first step in a huge research endeavor to unpick the outcomes of tens of thousands of ...
Jul 5, 2024
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Drug development is typically slow: the pipeline from basic research discoveries that provide the basis for a new drug to clinical trials to production of a widely available medicine can take decades. But decades can feel ...
Jun 27, 2024
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Transcription factors (TFs) are proteins that bind to specific DNA sequences, regulating the transcription of genetic information from DNA to messenger RNA (mRNA). These proteins play a pivotal role in the regulation of gene ...
