Genetics

Ancient epigenetic changes silence cancer-linked genes

An epigenetic change, a form of DNA control, that deactivates some genes linked to cancer late in human development has been conserved for more than 400 million years, new research led by the Garvan Institute of Medical Research ...

Medical research

A moderate dose of novel form of stress promotes longevity

A newly described form of stress called chromatin architectural defect, or chromatin stress, triggers in cells a response that leads to a longer life. Researchers at Baylor College of Medicine and the Houston Methodist Research ...

Oncology & Cancer

How human genetic data is helping dogs fight cancer

Some of what we learn through the compassionate treatment of dogs with cancer goes on to help human patients. Now a study by researchers at University of Colorado Cancer Center and Colorado State University Flint Animal Cancer ...

Genetics

Gene networks reveal transition from healthy to failing heart

Scientists investigating heart failure have been limited to studying diseased heart tissue in the lab—understandably, as people don't tend to pluck out a healthy heart for the sake of research. But now, scientists with ...

Oncology & Cancer

Signature of an ineffective immune response to cancer revealed

Our immune system is programmed to destroy cancer cells. Sometimes it has trouble slowing disease progression because it doesn't act quickly or strongly enough. In a study published in The Journal of Clinical Investigation, ...

Medical research

Rapamycin retards epigenetic ageing of keratinocytes

Cessation, or even retardation of the ageing process is an appealing notion that has captured the imagination of humans for millennia. Even if it were possible to rejuvenate our bodies or retard the ageing process, how do ...

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