Oncology & Cancer

Algorithm turns cancer gene discovery on its head

A method for finding genes that spur tumor growth takes advantage of machine learning algorithms to sift through reams of molecular data collected from studies of cancer cell lines, mouse models and human patients.

Medical research

Researchers identify gene with functional role in aging of eye

A lengthy-named gene called Elongation of Very Long Chain Fatty Acids Protein 2 or ELOVL2 is an established biomarker of age. In a new paper, published online January 14, 2020 in the journal Aging Cell, researchers at University ...

Diseases, Conditions, Syndromes

Neuropeptide reduces epileptic seizures in human brain tissue

One challenge facing researchers who study brain diseases is that for understandable reasons it is difficult to obtain human brain tissue for experiments. For that reason, experimental models are used, such as rodent studies, ...

Genetics

Using gene therapy to treat chronic traumatic encephalopathy

A new study shows the feasibility of using gene therapy to treat the progressive neurodegenerative disorder chronic traumatic encephalopathy (CTE). The study, which demonstrated the effectiveness of direct delivery of gene ...

Oncology & Cancer

Researchers identify new therapeutic target for colorectal cancer

Researchers at the University of Toronto have identified a key protein that supports the growth of many colorectal cancers. The study, which will be published December 27 in the Journal of Cell Biology, reveals that a protein ...

Medical research

A new gene therapy strategy, courtesy of Mother Nature

Scientists have developed a new gene-therapy technique by transforming human cells into mass producers of tiny nano-sized particles full of genetic material that has the potential to reverse disease processes.

Neuroscience

The genetic signature of memory

Despite their common involvement in memory, the human cortex and subcortex display a distinct collection of gene signatures. The work recently published in eNeuro increases our understanding of how the brain creates memories ...

Oncology & Cancer

'Junk DNA' affects inherited cancer risk

A person's risk of developing cancer is affected by genetic variations in regions of DNA that don't code for proteins, previously dismissed as 'junk DNA', according to new research published in the British Journal of Cancer ...

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