CRISPR's potential to prevent or treat disease is widely recognized. But the gene-editing technology can also be used as a research tool to probe and understand diseases.
Apr 26, 2021
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DNA ligase proteins, which facilitate the formation of bonds between separate strands of DNA, play critical roles in the replication and maintenance of DNA. The human genome encodes three different DNA ligase proteins, but ...
Apr 16, 2021
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Using an innovative protein-based approach, researchers at the Atlanta Veterans Affairs Medical Center and nearby Emory University have found genes and corresponding proteins that could point the way to new depression treatments.
Apr 12, 2021
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Researchers at the Human Genome and Stem Cell Research Center (HUG-CELL), hosted by the University of São Paulo's Institute of Biosciences (IB-USP) in Brazil, have developed a technique to reconstruct and produce livers ...
Apr 6, 2021
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A new analysis of the entire genetic makeup of more than 53,000 people offers a bonanza of valuable insights into heart, lung, blood and sleep disorders, paving the way for new and better ways to treat and prevent some of ...
Apr 5, 2021
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A new review of existing evidence proposes eight hallmarks of environmental exposures that chart the biological pathways through which pollutants contribute to disease: oxidative stress and inflammation, genomic alterations ...
Mar 5, 2021
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COVID-19 is only the latest infectious disease to have had an outsized impact on human life. A new study employing ancient human DNA reveals how tuberculosis has affected European populations over the past 2,000 years, specifically ...
Mar 4, 2021
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Evolutionary forces drive a glaring gender imbalance in the occurrence of many health conditions, including autism, a team of genetics researchers has concluded.
Mar 3, 2021
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Researchers in the Muir Lab at Princeton University's Department of Chemistry have completed the first comprehensive analysis of cancer-associated histone mutations in the human genome, featuring both biochemical and cellular ...
Mar 1, 2021
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Researchers at the University of Maryland School of Medicine (UMSOM) co-authored a study, published today in the journal Science, that details the sequencing of 64 full human genomes. This reference data includes individuals ...
Feb 26, 2021
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