A large team of researchers affiliated with a host of institutions in the U.S., France and Spain has found that the drug plitidepsin worked better at treating COVID-19 than did remdesivir in a lab setting. In their paper ...
When SARS-CoV-2 began its furious spread around the globe, it took scientists only a few months to develop the first tools to study or neutralize the virus. What's been missing until now, however, are reliable methods to ...
Jan 21, 2021
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Researchers demonstrate in a proof-of-concept study that a phage-based inhalation delivery system for vaccines generates potent antibody responses in mice and non-human primates, without causing lung damage. The findings ...
Dec 10, 2020
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When Anna Greka, an institute member at the Broad Institute of MIT and Harvard and a physician at Brigham and Women's Hospital, volunteered to help care for patients with COVID-19 at the peak of Boston's springtime surge, ...
Nov 18, 2020
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Chronic obstructive pulmonary disease (COPD) is one of the most common and deadly diseases worldwide. Until now, COPD was not curable. Researchers at Helmholtz Zentrum München and at the German Cancer Research Center (DKFZ) ...
Nov 4, 2020
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For the first time, researchers have successfully created airway basal stem cells in vitro from induced pluripotent stem cells by reprogramming blood cells taken from patients. Given that airway basal cells are defined as ...
Oct 23, 2020
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An international collaboration of researchers across more than 80 countries has come to the conclusion that chloroquine (CQ) and hydroxchloroquine (HCQ) are unlikely to provide clinical benefit against COVID-19. In a new ...
Aug 27, 2020
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The global effort to quickly develop drugs and vaccines for COVID-19 has been hampered by limited numbers of laboratory mice that are susceptible to infection with SARS-CoV-2, the virus that causes COVID-19. Now, researchers ...
Jun 10, 2020
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A mouse model of infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) reproduces features observed in human patients, researchers report May 26 in the journal Cell Host & Microbe. Using CRISPR/Cas9 ...
May 27, 2020
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A team of researchers from Germany, Switzerland, Sweden and Australia has found that a substance isolated from roundworm larvae was able to reduce inflammation in the airways of mice. In their paper published in the journal ...
