Diseases, Conditions, Syndromes

Synthetic molecule 'kicks and kills' some persistent HIV in mice

Scientists have designed a synthetic molecule that can reactivate dormant human immunodeficiency virus (HIV) in mice and lead to the death of some of the infected cells, according to a study published in PLOS Pathogens.

Genetics

New technique searches 'dark genome' for disease mutations

When doctors can't find a diagnosis for patient's disease, they turn to genetic detectives. Equipped with genomic sequencing technologies available for less than 10 years, these sleuths now routinely search through a patient's ...

Immunology

How the human body first fights off pathogens

People constantly encounter viruses, bacteria or parasites. Fortunately, our skin, the specialized lining of our guts and other parts of our body that are exposed to the outside world prevent them from entering. When a pathogen ...

Diseases, Conditions, Syndromes

Parasite protein could help inform new anti-tuberculosis strategies

Proteins produced by the parasite that causes toxoplasmosis may be involved in immune system processes that can help fight mycobacteria, according to a new study. The findings, published in PLOS Pathogens, suggest that these ...

Medical research

A new wave of antimalarial drugs

Malaria caused by the parasite Plasmodium falciparum remains a major public health problem worldwide. As a continuation of previous research targeting Hsp90, a universal molecular chaperone performing vital functions both ...

Medical research

Researchers test new pathogen detection technology

Patients who are undergoing treatment for diseases such as cancer often face the added challenge of a compromised immune system, which can be a toll both of their condition and the drugs used to treat it, leaving them vulnerable ...

Medical research

Team improves its sepsis therapeutic device

Last year, a Wyss Institute team of scientists described the development of a new device to treat sepsis that works by mimicking our spleen. It cleanses pathogens and toxins from blood circulating through a dialysis-like ...

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