Medical research

Scientists illuminate mechanism of common drug target

Roughly a third of all drugs approved by the U.S. Food and Drug Administration target a large family of biomolecules, known as G protein-coupled receptors (GPCRs), whose job is to trigger cellular responses to extracellular ...

Neuroscience

Findings open way for personalized multiple sclerosis treatment

Currently available therapies to treat multiple sclerosis (MS) lack precision and can lead to serious side effects. Researchers at Karolinska Institutet in Sweden have now developed a method for identifying the immune cells ...

Medications

New therapeutic option for head and neck carcinomas

The various manifestations of head and neck carcinomas rank sixth in frequency worldwide and are fatal for about half a million people every year. In a quarter of cases, head and neck squamous cell carcinoma (HNSCC) is caused ...

Medications

Nasal antiviral blocks SARS-CoV-2 infection in mice

SARS-CoV-2, the virus that causes COVID-19, has continuously mutated since it emerged in late 2019. This rapid evolution poses challenges for vaccines and treatments designed to target the virus. A booster shot is now needed ...

Diseases, Conditions, Syndromes

Coronaviruses evolve to recognize glycans of their host species

When coronaviruses jump species—as SARS-CoV-2 is thought to have done from bats or pangolins to humans—they must quickly adapt to their new host. For example, they must evolve to recognize the unique sugar molecules, ...

Diseases, Conditions, Syndromes

Immunologists unravel battle plans of deadly coronaviruses

Immunologists from Trinity, who have worked on coronaviruses for the past decade, have just unraveled new secrets behind the viruses' battle plans—providing new insights into how these deadly viruses sometimes win the war ...

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