Genetics

Researcher hopes to use epigenome editing to fight disease

(Medical Xpress)—Growing up in Iowa, Dr. Eric Mendenhall says biology always "came really easily" to him. But other than becoming a doctor, which he wasn't interested in, he didn't know what to do with a degree in the field. ...

Oncology & Cancer

Particular donor genotype lowers leukemia relapse rate

(HealthDay)—Patients with acute myeloid leukemia who receive a stem cell transplant from a donor with activating killer-cell immunoglobulin-like receptor (KIR) genotype KIR2DS1, which has ligand specificity for human leukocyte ...

Medical research

Insights into the ecology of the microbiome

The microbiome is like a fingerprint: every person's community of microbes is complex and unique. But the underlying dynamics, the interactions between the microbes that shape these microbial ecosystems, may have something ...

Cardiology

Scientists show how cells react to injury from open-heart surgery

Cedars-Sinai Heart Institute investigators have learned how cardiac muscle cells react to a certain type of injury that can be caused by open-heart surgery. The findings point to a new potential way to help these hearts recover ...

Immunology

Use of stem cells, conditioning induces immune tolerance

(HealthDay) -- A novel approach using a bioengineered mobilized cellular product enriched with hematopoietic stem cells (HSCs) and tolerogenic graft facilitating cells (FCs) in combination with nonmyeloablative conditioning ...

Medical research

Purified pituitary tissue generated from stem cells

Researchers have successfully converted human pluripotent stem cells into purified pituitary cells that aggregated into hormone-secreting organoids. As reported June 8 in the journal Stem Cell Reports, transplantation of ...

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