Type 1 diabetes occurs when a person's own immune system destroys insulin-producing beta cells in the pancreas. In recent years, scientists have learned how to grow large volumes of replacement beta cells, but the researchers ...
Jul 27, 2020
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Researchers in Germany have developed a transgenic mouse that could help scientists identify new influenza virus strains with the potential to cause a global pandemic. The mouse is described in a study, "In vivo evasion of ...
Apr 10, 2017
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A cancer tumor's ability to mutate allows it to escape from chemotherapy and other attempts to kill it. So, encouraging mutations would not be a logical path for cancer researchers. Yet a Mayo Clinic team and their collaborators ...
Feb 7, 2020
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Mouse models of human diseases are essential research tools that are widely used in the medical sciences to increase our understanding of the pathogenesis and pathophysiology of various diseases, and to search for cures. ...
Aug 4, 2014
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New research sheds light on common pathogenic mechanisms shared by Huntington's disease (HD) and HD-like disorders. The study, published by Cell Press in the May 12, 2011, issue of the journal Neuron, uses a new transgenic ...
May 11, 2011
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A key mechanism of cadmium-linked inflammation that increases severity and mortality of lung infections has been described, offering a promising therapeutic target to limit lung injury and death.
Apr 20, 2023
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A team of researchers at the Gladstone Institutes uncovered a new strategy to treat heart failure, a leading contributor to mortality and healthcare costs in the United States. Despite widespread use of currently-approved ...
May 17, 2017
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Despite the strong association between diabetes and dementia, how insulin deficiency affects brain function remains unclear. A recent study published in The FASEB Journal used a mouse model to investigate this mechanism.
Jan 24, 2019
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Princeton University researchers Qiang Ding, Alexander Ploss, and colleagues have identified one of the mechanisms by which Zika virus (ZIKV) circumvents immune control to replicate in human cells. The paper detailing this ...
Jun 19, 2018
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The bacteria living in the intestine consist of some 500 to 1000 different species. They make up what is known as the intestinal flora, which plays a key role in digestion and prevents infections. Unlike pathogens that invade ...
Oct 13, 2021
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